Stanozolol is perhaps the only drug (except, danazol), which is able to interact with androgen receptors in the microsomal level (that is, with the androgen receptors located inside the “fragments” – microsomes formed during cell division, often these receptors called microsomal receptors – MR ). Such accession to the MR adipose tissue can significantly enhance the process of lipolysis. In combination with trenbolone also have a pronounced fat burning abilities, stanozolol is able to give a good effect, surpassing even the effect of the combination of “caffeine + ephedrine.” To enhance the fat burning process commonly used systemic injection of the drug.
Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease include osteolytic-induced hypercalcemia.
Anabolic steroids effect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred during anabolic steroid therapy.
The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]