During conventional pharmacologic dose corticosteroid therapy, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation. Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone (10 mg) as opposed to a quarter of that dose administered every six hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used. Further, it has been shown that a single dose of certain corticosteroids will produce adrenal cortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenal cortical suppression for 1¼ to 1½ days following a single dose) and thus are recommended for alternate day therapy.
"Steroid" is the name given to a chemical compound with a specific structure. In everyday speech, the term steroid is applied to several medications that share this structure; however, these medications have very different uses. Anabolic steroids are a class of drug that mimic the effects of male sex hormones called androgens which stimulate muscle growth and secondary male sex characteristics. They are often abused by bodybuilders and other athletes to build muscle mass and so should be used with caution. When prescribed, oral steroids should be taken as directed. If you come across extra pills that haven't been taken, and are unsure if they are steroids, you can identify the pill based on its physical appearance, information on the bottle, or by consulting a professional.
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