An important factor in a high quality probiotic is its ability to survive through gastric acidity. If a probiotic has not been tested to survive gastric acidity and biliary salts then it may not reach the intestines which is where it needs to settle in order to exert its beneficial effects on the body. The strains in the OptiBac Probiotics range were developed to survive gastric acidity above (ie. more neutral than) pH 3. In-vitro trials on our probiotic strains show a 95 - 100% survival rate through gastric acidity at this pH level. Research from microbiologists shows that at mealtimes (and especially breakfast time) the stomach’s gastric acidity is naturally at pH 4 or above.
I only recently began taking Vitamin D3 with K2 MK-7. The only D3 with sufficient amounts of natural K2 I was able to find online and order is called “Buried Treasure – Liquid D3 with K2″. I take it early in the day for the simple reason that it’s replacing the D3 that should be made in our bodies when we’re exposed to the sun — which is during the day. It seems unnatural to me to take D3 at night when our system is going into rest and repair mode (and should not be working to absorb a vitamin it should have got earlier in the day), and I wonder if that’s why you and many others here are reporting sleep disturbances when taking D3 at night.